Globally, there are 120 million live births annually. 10% of those are born prematurely and 15% require intensive care in their first months of life, comprising high risk populations for developing brain injury due to impaired and/or variable blood flow to the brain. To reduce the risk of neurodevelopmental damage, there is a strong unmet need for improved monitoring of brain circulation.
Currently, no direct continuous measurement of cerebral blood flow exists.
Cimon Medical aims to solve this problem by providing a non-invasive, simple-to-use and affordable product, the NeoDoppler, that is built on the Cimon core technology and designed to be easily integrated into the clinical workflow.
Alternative methods either rely on an indirect measure of the blood flow or intermittent examinations by trained professionals.
The NeoDoppler system will include a stand-alone display unit that connects to an ultrasound scanner unit. For each new patient, a disposable ultrasound probe is attached to the patient using a tailored fixation accessory and connected to the scanner unit.
The probe and associated fixation accessory are designed to be compact and easy to place and attach over the fontanelle of the child by any pediatric nurse without the need for specialized training or ultrasound expertise. In order to minimize footprint the system is designed to operate together with existing monitoring and treatment equipment, as well as facilitating child-parent interaction.
The display unit will show the fluctuating blood flow in the brain of the patient throughout each heart cycle in real time, as well as relative derived measures that are more robust against patient movement.Together, these provide both acute information and long-term trends that allow clinicians to act early to prevent brain damage by timing medical interventions.
There are several patient groups that will benefit from monitoring with NeoDoppler including preterms that are especially vulnerable to fluctuations in cerebral blood flow and have an increased risk of brain damage; Neonates with congenital heart disease that need surgery due to significant hemodynamic defects also increasing the risk of brain damage; and full-term infants in need of intensive care such as babies with asphyxia, infections or congenital malformations that require surgery.